Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
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Indonesia insole ODM for global brands
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Custom graphene foam processing Taiwan
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Smart pillow ODM manufacturer Thailand
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Breathable insole ODM development China
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Vietnam foot care insole ODM expert
Ancient horses crossed over the Bering Land Bridge in both directions between North America and Asia multiple times during the Pleistocene. Credit: Illustration by Julius Csotonyi New findings show connections between the ancient horse populations in North America, where horses evolved, and Eurasia, where they were domesticated. A new study of ancient DNA from horse fossils found in North America and Eurasia shows that horse populations on the two continents remained connected through the Bering Land Bridge, moving back and forth and interbreeding multiple times over hundreds of thousands of years. The new findings demonstrate the genetic continuity between the horses that died out in North America at the end of the last ice age and the horses that were eventually domesticated in Eurasia and later reintroduced to North America by Europeans. The study has been accepted for publication in the journal Molecular Ecology and is currently available online. Paleontologist Aisling Farrell holds a mummified frozen horse limb recovered from a placer gold mine in the Klondike goldfields in Yukon Territory, Canada. Ancient DNA recovered from horse fossils reveals gene flow between horse populations in North America and Eurasia. Credit: Government of Yukon “The results of this paper show that DNA flowed readily between Asia and North America during the ice ages, maintaining physical and evolutionary connectivity between horse populations across the Northern Hemisphere,” said corresponding author Beth Shapiro, professor of ecology and evolutionary biology at UC Santa Cruz and a Howard Hughes Medical Institute investigator. The study highlights the importance of the Bering Land Bridge as an ecological corridor for the movement of large animals between the continents during the Pleistocene, when massive ice sheets formed during glacial periods. Dramatically lower sea levels uncovered a vast land area known as Beringia, extending from the Lena River in Russia to the MacKenzie River in Canada, with extensive grasslands supporting populations of horses, mammoths, bison, and other Pleistocene fauna. Paleontologists have long known that horses evolved and diversified in North America. One lineage of horses, known as the caballine horses (which includes domestic horses) dispersed into Eurasia over the Bering Land Bridge about 1 million years ago, and the Eurasian population then began to diverge genetically from the horses that remained in North America. The new study shows that after the split, there were at least two periods when horses moved back and forth between the continents and interbred, so that the genomes of North American horses acquired segments of Eurasian DNA and vice versa. “This is the first comprehensive look at the genetics of ancient horse populations across both continents,” said first author Alisa Vershinina, a postdoctoral scholar working in Shapiro’s Paleogenomics Laboratory at UC Santa Cruz. “With data from mitochondrial and nuclear genomes, we were able to see that horses were not only dispersing between the continents, but they were also interbreeding and exchanging genes.” Mitochondrial DNA, inherited only from the mother, is useful for studying evolutionary relationships because it accumulates mutations at a steady rate. It is also easier to recover from fossils because it is a small genome and there are many copies in every cell. The nuclear genome carried by the chromosomes, however, is a much richer source of evolutionary information. Alisa Vershinina works in the Paleogenomics Lab at UC Santa Cruz where ancient DNA is extracted from fossils for sequencing and analysis. Credit: UC Santa Cruz The researchers sequenced 78 new mitochondrial genomes from ancient horses found across Eurasia and North America. Combining those with 112 previously published mitochondrial genomes, the researchers reconstructed a phylogenetic tree, a branching diagram showing how all the samples were related. With a location and an approximate date for each genome, they could track the movements of different lineages of ancient horses. “We found Eurasian horse lineages here in North America and vice versa, suggesting cross-continental population movements. With dated mitochondrial genomes we can see when that shift in location happened,” Vershinina explained. The analysis showed two periods of dispersal between the continents, both coinciding with periods when the Bering Land Bridge would have been open. In the Middle Pleistocene, shortly after the two lineages diverged, the movement was mostly east to west. A second period in the Late Pleistocene saw movement in both directions, but mostly west to east. Due to limited sampling in some periods, the data may fail to capture other dispersal events, the researchers said. The team also sequenced two new nuclear genomes from well-preserved horse fossils recovered in Yukon Territory, Canada. These were combined with 7 previously published nuclear genomes, enabling the researchers to quantify the amount of gene flow between the Eurasian and North American populations. “The usual view in the past was that horses differentiated into separate species as soon as they were in Asia, but these results show there was continuity between the populations,” said coauthor Ross MacPhee, a paleontologist at the American Museum of Natural History. “They were able to interbreed freely, and we see the results of that in the genomes of fossils from either side of the divide.” The new findings are sure to fuel the ongoing controversy over the management of wild horses in the United States, descendants of domestic horses brought over by Europeans. Many people regard those wild horses as an invasive species, while others consider them to be part of the native fauna of North America. “Horses persisted in North America for a long time, and they occupied an ecological niche here,” Vershinina said. “They died out about 11,000 years ago, but that’s not much time in evolutionary terms. Present-day wild North American horses could be considered reintroduced, rather than invasive.” Coauthor Grant Zazula, a paleontologist with the Government of Yukon, said the new findings help reframe the question of why horses disappeared from North America. “It was a regional population loss rather than an extinction,” he said. “We still don’t know why, but it tells us that conditions in North America were dramatically different at the end of the last ice age. If horses hadn’t crossed over to Asia, we would have lost them all globally.” Reference: “Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge” by Alisa O. Vershinina, Peter D. Heintzman, Duane G. Froese, Grant Zazula, Molly Cassatt-Johnstone, Love Dalén, Clio Der Sarkissian, Shelby G. Dunn, Luca Ermini, Cristina Gamba, Pamela Groves, Joshua D. Kapp, Daniel H. Mann, Andaine Seguin-Orlando, John Southon, Mathias Stiller, Matthew J. Wooller, Gennady Baryshnikov, Dmitry Gimranov, Eric Scott, Elizabeth Hall, Susan Hewitson, Irina Kirillova, Pavel Kosintsev, Fedor Shidlovsky, Hao-Wen Tong, Mikhail P. Tiunov, Sergey Vartanyan, Ludovic Orlando, Russell Corbett-Detig, Ross D. MacPhee and Beth Shapiro, 10 May 2021, Molecular Ecology. DOI: 10.1111/mec.15977 This project was a large international collaborative effort involving researchers at multiple institutions working together to obtain DNA from fossils of ancient horses over a wide range of sites in Eurasia and North America. The coauthors include researchers from the University of Toulouse, France, the Arctic University of Norway, and other institutions in the United States, Canada, Sweden, Denmark, Germany, Russia, and China. This work was supported in part by the U.S. National Science Foundation, Gordon & Betty Moore Foundation, and the American Wild Horse Campaign.
Researchers found that people in REM sleep can communicate and engage in real-time interaction, comprehending questions and providing answers. Dreaming Minds Can Communicate in Real Time Dreams take us to what feels like a different reality. They also happen while we’re fast asleep. So, you might not expect that a person in the midst of a vivid dream would be able to perceive questions and provide answers to them. But a new study reported in the journal Current Biology on February 18, 2021, shows that, in fact, they can. “We found that individuals in REM sleep can interact with an experimenter and engage in real-time communication,” said senior author Ken Paller of Northwestern University. “We also showed that dreamers are capable of comprehending questions, engaging in working-memory operations, and producing answers. “Most people might predict that this would not be possible — that people would either wake up when asked a question or fail to answer, and certainly not comprehend a question without misconstruing it.” While dreams are a common experience, scientists still haven’t adequately explained them. Relying on a person’s recounting of dreams is also fraught with distortions and forgotten details. So, Paller and colleagues decided to attempt communication with people during lucid dreams. This photo shows Konkoly watching brain signals from a sleeping participant in the lab. Researchers are working to expand and refine two-way communications with sleeping people so more complex conversations may one day be possible. Credit: K. Konkoly “Our experimental goal is akin to finding a way to talk with an astronaut who is on another world, but in this case the world is entirely fabricated on the basis of memories stored in the brain,” the researchers write. They realized finding a means to communicate could open the door in future investigations to learn more about dreams, memory, and how memory storage depends on sleep, the researchers say. The researchers studied 36 people who aimed to have a lucid dream, in which a person is aware they’re dreaming. The paper is unusual in that it includes four independently conducted experiments using different approaches to achieve a similar goal. In addition to the group at Northwestern University in the U.S., one group conducted studies at Sorbonne University in France, one at Osnabrück University in Germany, and one at Radboud University Medical Center in the Netherlands. “We put the results together because we felt that the combination of results from four different labs using different approaches most convincingly attests to the reality of this phenomenon of two-way communication,” said Karen Konkoly, a PhD student at Northwestern University and first author of the paper. “In this way, we see that different means can be used to communicate.” This photo shows Mazurek in a full EEG rig just before a sleep session in the lab. The electrodes on his face will detect the movement of his eyes as he sleeps. Credit: C. Mazurek Understanding and Responding in Dreams One of the individuals who readily succeeded with two-way communication had narcolepsy and frequent lucid dreams. Among the others, some had lots of experience in lucid dreaming and others did not. Overall, the researchers found that it was possible for people while dreaming to follow instructions, do simple math, answer yes-or-no questions, or tell the difference between different sensory stimuli. They could respond using eye movements or by contracting facial muscles. The researchers refer to it as “interactive dreaming.” Konkoly says that future studies of dreaming could use these same methods to assess cognitive abilities during dreams versus wake. They also could help verify the accuracy of post-awakening dream reports. Outside of the laboratory, the methods could be used to help people in various ways, such as solving problems during sleep or offering nightmare sufferers novel ways to cope. Follow-up experiments run by members of the four research teams aim to learn more about connections between sleep and memory processing, and about how dreams may shed light on this memory processing. Reference: “Real-time dialogue between experimenters and dreamers during REM sleep” by Karen R. Konkoly, Kristoffer Appel, Emma Chabani, Anastasia Mangiaruga, Jarrod Gott, Remington Mallett, Bruce Caughran, Sarah Witkowski, Nathan W. Whitmore, Christopher Y. Mazurek, Jonathan B. Berent, Frederik D. Weber, Basak Türker, Smaranda Leu-Semenescu, Jean-Baptiste Maranci, Gordon Pipa and Isabelle Arnulf, 18 February 2021, Current Biology. DOI: 10.1016/j.cub.2021.01.026 This work was supported by the Mind Science Foundation, National Science Foundation, Société Française de Recherche et Médecine du Sommeil (SFRMS), Hans-Mühlenhoff-Stiftung Osnabrück, a Vidi grant from the Netherlands Organisation for Scientific Research (NWO), and COST Action CA18106 supported by COST (European Cooperation in Science and Technology). Students in Paller’s lab group have also developed a smartphone app that aims to make it easier for people to achieve lucidity during their dreams: https://pallerlab.psych.northwestern.edu/dream
An international team has mapped the genome of Zygnema algae, ancestors of terrestrial plants, uncovering key evolutionary adaptations. This research could impact future studies in plant biology and environmental sustainability. Researchers have decoded the genomic sequence of Zygnema algae, revealing insights into the evolutionary transition from aquatic to terrestrial plant life. This breakthrough enhances our understanding of plant adaptation mechanisms and offers a basis for future studies in environmental resilience and bioenergy. Plant life first emerged on land about 550 million years ago, and an international research team co-led by University of Nebraska–Lincoln computational biologist Yanbin Yin has cracked the genomic code of its humble beginnings, which made possible all other terrestrial life on Earth, including humans. The team — about 50 scientists in eight countries – has generated the first genomic sequence of four strains of Zygnema algae, the closest living relatives of land plants. Their findings shed light on the ability of plants to adjust to the environment and provide a rich basis for future research. The study was published recently in the journal Nature Genetics. Evolutionary Insights Into Terrestrial Plant Life “This is an evolutionary story,” said Yin, who led the research team with a scientist from Germany. “It answers the fundamental question of how the earliest land plants evolved from aquatic freshwater algae.” Yin’s lab in the Nebraska Food for Health Center and the Department of Food Science and Technology has a long history of studying plant cell wall carbohydrates, a major component of dietary fibers for humans and farm animals; lignocelluloses for biofuel production; and natural barriers to protect crops from pathogens and environmental stresses. Computational biologist Yanbin Yin (right) and postdoctoral researcher Xuehan Feng review algae samples. Credit: Craig Chandler/University Communication and Marketing;/University of Nebraska-Lincoln All current plant life on land burst from a one-off evolutionary event known as plant terrestrialization from ancient freshwater algae. The first land plants, known as embryophyta within the clade of streptophyta, emerged on land about 550 million years ago — their arrival fundamentally changing the surface and atmosphere of the planet. They made all other terrestrial life, including humans and animals, possible by serving as an evolutionary foundation for future flora and food for fauna. Pioneering Genomic Techniques in Algal Research The researchers worked with four algal strains from the genus Zygnema — two from a culture collection in the United States and two from Germany. Scientists combined a range of cutting-edge DNA sequencing techniques to determine the entire genome sequences of these algae. These methods enabled scientists to generate complete genomes for these organisms at the level of whole chromosomes — something that had never been done before on this group of algae. Comparing the genomes with those of other plants and algae led to the discovery of specific overabundances of cell wall enzymes, signaling genes, and environmental response factors. Unique Features of Zygnema Algae A unique feature of these algae revealed by microscopic imaging — performed at the University of Innsbruck in Austria, the Universität Hamburg in Germany and UNL’s Center for Biotechnology — is a thick and highly sticky layer of carbohydrates outside the cell walls, called the mucilage layer. Xuehuan Feng, the first author of the paper and a Husker postdoctoral research associate, developed a new and effective DNA extraction method to remove this mucilage layer for high purity and high molecular DNAs. “It is fascinating that the genetic building blocks, whose origins predate land plants by millions of years, duplicated and diversified in the ancestors of plants and algae and, in doing so, enabled the evolution of more specialized molecular machinery,” said Iker Irisarri of the Leibniz Institute for the Analysis of Biodiversity Change and co-first author of the paper. The team’s other co-leader, Jan de Vries of the University of Göttingen, said, “Not only do we present a valuable, high-quality resource for the entire plant scientific community, who can now explore these genome data, our analyses uncovered intricate connections between environmental responses.” Exploring Environmental Adaptations in Algae The four multicellular Zygnema algae belong to the class Zygnematophyceae, the closest living relatives of land plants; it is a class of freshwater and semi-terrestrial algae with more than 4,000 described species. Zygnematophyceae possess adaptations to withstand terrestrial stressors, such as desiccation, ultraviolet light, freezing, and other abiotic stresses. The key to understanding these adaptations is the genome sequences. Before this paper, genome sequences were only available for four unicellular Zygnematophyceae. Implications for Science and Society Yin said this research aligns with one of the National Science Foundation’s 10 Big Ideas — “Understanding the Rules of Life” — to address societal challenges, from clean water to climate resilience. The discovery also holds significance in applied sciences, such as bioenergy, water sustainability and carbon sequestration. “Our gene network analyses reveal co-expression of genes, especially those for cell wall synthesis and remodifications that were expanded and gained in the last common ancestor of land plants and Zygnematophyceae,” Yin said. “We shed light on the deep evolutionary roots of the mechanism for balancing environmental responses and multicellular cell growth.” The international research collaboration includes about 50 researchers from 20 research institutions in eight countries — the United States, Germany, France, Austria, Canada, China, Israel and Singapore. Other Husker researchers on the team are Chi Zhang, professor of biological sciences, and Jeffrey Mower, professor of agronomy and horticulture. Reference: “Genomes of multicellular algal sisters to land plants illuminate signaling network evolution” by Xuehuan Feng, Jinfang Zheng, Iker Irisarri, Huihui Yu, Bo Zheng, Zahin Ali, Sophie de Vries, Jean Keller, Janine M. R. Fürst-Jansen, Armin Dadras, Jaccoline M. S. Zegers, Tim P. Rieseberg, Amra Dhabalia Ashok, Tatyana Darienko, Maaike J. Bierenbroodspot, Lydia Gramzow, Romy Petroll, Fabian B. Haas, Noe Fernandez-Pozo, Orestis Nousias, Tang Li, Elisabeth Fitzek, W. Scott Grayburn, Nina Rittmeier, Charlotte Permann, Florian Rümpler, John M. Archibald, Günter Theißen, Jeffrey P. Mower, Maike Lorenz, Henrik Buschmann, Klaus von Schwartzenberg, Lori Boston, Richard D. Hayes, Chris Daum, Kerrie Barry, Igor V. Grigoriev, Xiyin Wang, Fay-Wei Li, Stefan A. Rensing, Julius Ben Ari, Noa Keren, Assaf Mosquna, Andreas Holzinger, Pierre-Marc Delaux, Chi Zhang, Jinling Huang, Marek Mutwil, Jan de Vries and Yanbin Yin, 1 May 2024, Nature Genetics. DOI: 10.1038/s41588-024-01737-3 Funding for UNL’s portion of the research came primarily from Yin’s NSF CAREER award, the Nebraska Tobacco Settlement Biomedical Research Enhancement Fund, the National Institutes of Health, and the U.S. departments of Agriculture and Energy. Funding: U.S. National Science Foundation, Nebraska Tobacco Settlement Biomedical Research Development Fund, Research & Artistry Fund of Northern Illinois University, Joint Genome Institute, U.S. Department of Agriculture, NIH/National Institutes of Health, German Research Foundation, European Research Council, Austrian Science Fund, Bill and Melinda Gates Foundation, UK Foreign, Commonwealth and Development Office, Laboratoires d’Excellence
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